The Best D-Ribose Supplements for Energy Boosting

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Top Pick

One of the greatest appeals of supplementing for fitness lies in boosting energy levels. Stimulants are a popular go-to when it comes to pre-workouts and performance—but not everyone can tolerate them.

If that’s the case, D-ribose could be the way forward.

This guide will explain the advantages, drawbacks and the best D-ribose supplements available.

The Best D-Ribose Energy Boosting Supplements

Here are my picks of the top-rated D-ribose products available.

1. Nutricost D-Ribose

Nutricost is another well-respected supplement producer that offers a pure D-ribose product—with zero fillers.

Inside the 500-gram (1.1lbs) tub you’ll find 100 servings providing 5000 mg of D-ribose each. This should give you around a months supply on maximum dosage strategies.

However, potentially it could last up to 100 days—great for those looking at long term supplementation.

Directions for use: Consume one scoop up to three times per day, which means you’ll receive a maximum of 15000mg. For training days—up to one scoop before exercise.

  • Long-lasting supply.
  • Effective dosage level.
  • Scoop included for accurate servings.
  • FDA registered and GMP compliant facility.
  • Independently lab tested.
  • It doesn’t mix well.

2. BulkSupplements D-Ribose Powder

In my opinion, if you are looking for a no-fuss product, BulkSupplements could be a good option.

They offer an unadulterated D-ribose powder—nothing extra whatsoever has been added. It’s even lab tested for purity, strength, and quality—emphasizing that it’s free of fillers.

Each pouch contains 100 servings of 5000 mg which is roughly a one month supply.

Directions for use: take one scoop three times per day, which equates to a total dosage of 15000 mg.

I feel BulkSupplements is a respected brand and its D-ribose supplement doesn’t disappoint.

  • 100 percent pure D-ribose.
  • Free from common allergens.
  • Taste isn’t overpowering.
  • Generous portion.
  • Some users felt it didn’t dissolve as well as anticipated.

3. Doctor’s Best D-Ribose

I believe this product is possibly ideal for those people who seek backing from science. This is because it’s clinically researched and also independently tested for purity and efficacy.

Furthermore, the manufacturers use a patented form of D-ribose—Bioenergy ribose, which claims to be the only formulation that has achieved “GRAS” (generally recognized as safe) status.

It’s powder form with a solid serving suggestion of 5000 mg. Plus the product includes a total of 50 servings per 250-gram container—a 25-day supply.

Directions for use: one scoop twice per day which amounts to 10000 mg.

  • Science-backed supplement.
  • GMP Certified.
  • It mixes well into juices.
  • Suitable for vegans and vegetarians.
  • Some users felt the design of the tub isn’t practical.

4. Jarrow Formulas Ribose

I feel that this product has been designed with the athlete in mind—its focus is geared towards supporting recovery, energy, and stamina.

You receive 90 servings of 2000 mg (30 days supply), which is a milder dose than my first two choices, yet still a decent quota. This might be a good supplement for those starting out.

The powder-formed product enlists the trademarked Bioenergy D-ribose as its one and only source of the compound. It’s also free from soy, dairy, and gluten, plus suitable for plant-based diets.

Directions for use: one scoop up to three times per day, giving you an overall dose of 6000 mg.

  • Lighter dosage strategy.
  • Aimed towards the sports enthusiast.
  • Non-GMO NSF approved.
  • Great quality.
  • Side effects have been reported by some users.

5. WellBodyNaturals Pure D-Ribose Powder

What strikes me most about this supplement is the sheer volume of it—I think this could be suited to those that love to bulk buy.

The reason being—you’ll get 200 servings from this 1kg (2.2lbs) supply, complete with a serving size of 5000 mg. It’s also lab-tested which is appreciated.

It’s a clean formulation, with zero other ingredients, fillers or additives—just straight pharmaceutical grade D-ribose.

Directions for use: take one to three servings per day or as needed, the intake will mount up to 15000 mg.

  • Impressive volume.
  • Lab tested.
  • Free of fillers and additives.
  • The powder is ultra fine, which some found tricky to prepare.

Informational guide to D-Ribose (Energy Boosting) Supplements

What Is D-Ribose?

To understand how D-ribose can help you, we have to take a look at the human body.

The mitochondria—is known aptly as the powerhouses of our cells. They’re called such because their main purpose is to produce ATP (Adenosine triphosphate)—best described as energy currency.

ATP is what fuels your cells, and your body requires it to perform almost every single task imaginable—including muscle contractions.

For instance, take a lightbulb. If it’s not connected to an energy source—it won’t work.

Keeping with that analogy. As time goes by the light bulb might grow dim, short circuit, or burn out until it stops working, whether plugged in or not. Your body is quite the same. Aging, illness and other disruptions can inhibit ATP production.

That’s where D-ribose comes in. It’s a simple sugar that’s naturally occurring in our bodies. It’s known to combat mitochondrial dysfunction, restoring sufficient production of ATP to keep your body running—and muscles moving.

Here’s a short video explaining the basics of ATP.

The Advantages of D-Ribose

D-ribose is a carbohydrate that can be found in a range of foods including:

  • Meat.
  • Poultry.
  • Seafood.
  • Dairy.
  • Vegetables.

However, our foods don’t contain a sufficient supply of it. This could be one of the reasons why so many people struggle with fatigue, even on a balanced and healthy diet.

Supplementing D-ribose is an easy and often affordable way to ensure your body meets its own energy demands. While in terms of fitness, there are even more benefits you may wish to take note of.

Restores and Increases Energy Levels

When tiredness and fatigue begin to set in, it usually means the end of your training session. More often than not your body says no but your mind is thinking otherwise.

As D-ribose powers your cells, maintaining its prominence in your body can reduce or eliminate fatigue and the symptoms that come with it.

In fact, two of the most common uses are for treating chronic fatigue and fibromyalgia. Studies suggest D-ribose increased energy levels by up to 45 percent.

Advantages of using D-ribose to replenish energy is that it could improve other aspects of your life too—better sleep quality and mental clarity. Both of these elements count towards improved training sessions.

This, alongside the fact that it’s good for cardiovascular function, could enhance your stamina and performance.

Improves Muscle Strength and Recovery

With all forms of physical activity, the muscles are exposed to oxidative stress. D-ribose has been shown to reduce the free radical offensive, which suggests could play a part in reducing muscle damage.

What’s more, as D-ribose replenishes cellular energy reserves, ATP stores don’t require time to recuperate—the body has the fuel ready and waiting which accelerates post-workout recovery times.

Another study shows that it could also boost muscle strength.

May Assist Weight Loss

Although research is limited, D-ribose has shown to suppress weight gain.

How Much and When to Take D-Ribose?

For larger doses, D-ribose is most convenient in powder form. It’s not uncommon to use D-ribose as a sweetener, so there is freedom for creativity in how you consume it.

There isn’t an official dietary reference intake (DRI) for D-ribose, hence, how much to consume is your decision. Although it’s recommended to take smaller doses more often for maximum effect.

For the average healthy guy or girl wanting to boost training, consensus points towards a daily serving of 5 grams. However, for the hardcore heavy lifter or extreme cardio bunny up to 15 grams could be required.

If you do feel you need to supplement multiple times a day, schedule it with mealtimes. Alternatively, treat D-ribose as you would a pre-workout—take between 30 minutes to one hour before training.

D-Ribose Side Effects

It’s not common for D-ribose to induce side effects, but there is still a chance. These include:

  • Nausea.
  • Stomach cramps.
  • Diarrhea.
  • Headaches.

One of the most significant is that D-ribose lowers your blood sugar—it’s not suitable for diabetics. You should also take care not to mix it with other medications or treatment that replicate similar effects.

Another consideration is that D-ribose interferes with uric acid levels, and might increase your risk of developing kidney infections and gout.

In terms of pregnancy or breastfeeding, more research is needed to determine whether or not D-ribose is safe. There is also uncertainty regarding potential side-effects following long-term supplementation.

Remember to always pay attention to the contraindications and warnings of the supplement you choose. It’s advisable to consult a medical practitioner before commencing supplementation.


We can produce D-ribose naturally, but over time our reserves deplete. Supplementing can improve our energy, quality of life and ultimately our fitness performance.

All of the products reviewed are valid contenders for replenishing ATP stores and taking your training to the next level.

However, BulkSupplement’s D-ribose powder is the one that stands out for me. It’s manufactured by a well-respected company, offers an effective serving suggestion and its purity is reinforced by independent testing.